This Galaxy workflow takes a list of tumor/normal sample pair variants in VCF format and 1. annotates them using the ENSEMBL Variant Effect Predictor and custom annotation data 2. turns the annotated VCF into a MAF file for import into cBioPortal 3. generates human-readable variant- and gene-centric reports The input VCF is expected to encode somatic status, somatic p-value and germline p-value of each variant in varscan somatic format, i.e., via SS, SPV and GPV INFO keys, respectively.